Rev. Soc. Bras. Enferm. Ped.2018;18(1):37-42.
Therapeutic hypothermia in newborns with hipoxic-ischemic encephalopathy: Integrative review
DOI: 10.31508/1676-3793201800006
Abstract
Objective
To seek evidence and associations of the neuroprotective mechanism of therapeutic hypothermia in newborns. Research question was: does therapeutic hypothermia reduce damage to the central nervous system and enhance neuroplasticity in newborns with hypoxic-ischemic encephalopathy?
Methods
Research with inclusion of articles with available summaries and free online access, related to the therapeutic hypothermia in newborn with encephalopathy, in the databases BDENF, MEDLINE, LILACS and SciELO.
Results
Ten articles were framed within the interest of research. The good prognosis of therapy was highlighted; less hospitalization time; Successfully intubation after 24 hours of the end of the exhibition; Reduction of sequelae and delay of neuropsicomotor development, and ultimately the reduction of the mortality rate.
Conclusion
Therapeutic hypothermia is safe and effective in reducing complications and mortality in newborns with hypoxic-ischemic encephalopathy, besides being a promising tool for humanized care in newborns with encephalopathy.
Keywords: Encephalopathy; Hypothermia; Newborn