Abstract The objective of this study was to identify the information needs of adolescents with cancer. Interviews were conducted with 12 adolescents treated in specialized oncology services in São Paulo city. Data were analyzed using the content analysis method. The results indicate five categories that represent the information needs of adolescents with cancer: diagnosis and treatment of cancer, the cancer experience, social issues, family experience and uncertainties. The study demonstrates that the extent to which adolescents have their doubts clarified, […]