Rev. Soc. Bras. Enferm. Ped.2022;22:eSOBEP2022001.
Treatment of diaper dermatitis associated with the antibiotic therapy in hospitalized children: systematic review
DOI: 10.31508/1676-379320220001
Abstract
Objective
To investigate, among the available treatments, the best levels of evidence for the treatment of diaper dermatitis associated with the use of antibiotic therapy.
Methods
Systematic review carried out in August 2020, in MEDLINE/Pubmed, CINAHL, SCOPUS and Web of Science databases, with the descriptors: Newborn, Infant, Diaper Rash, Therapeutics. Melnyk and Fineout-Overholt were used to level the evidence. Single-arm meta-analyses of event rates were performed using the random effects model with logit transformation. Heterogeneity was assessed by the chi-square (x2) and i-square (I2) tests.
Results
Nine publications were included. Natural therapies with human milk, honey, calendula, olive ointment, Aloe vera and Magnesium 2% stand out. Followed by 1% hydrocortisone, 0.05% clobetasone butyrate, zinc oxide paste and nystatin cream in the fungal infection.
Conclusion
Better recovery rates from diaper dermatitis involved 1% hydrocortisone, olive ointment, human milk, calendula and honey mixture.