Abstract Objective To assess the feasibility of conducting a randomized clinical trial to evaluate the effectiveness of virtual reality on pain perception in children undergoing peripheral intravenous insertion, compared to traditional clinical method. Methods A pilot randomized clinical trial involved two groups: intervention with virtual reality and control with traditional clinical method during peripheral catheterization. Participants were children aged 4-14 years, who were clinically stable, conscious, and undergoing elective procedures. The feasibility outcomes included eligibility, recruitment, protocol fidelity, retention, missing […]